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99% Purity Verified

Third-Party Tested by Janoshik • HPLC & MS

UltraBiomed™ HGH 36 IU

HGH is a recombinant polypeptide of the single-chain cytokine class, chemically a protein of 191 amino acids with two internal disulfide bridges. In scientific research, it is studied as a model compound for receptor dimerization and protein conformation, and as a reference standard in analytical protein work. This compound is offered as freeze-dried lyophilisate in a single sealed vial containing 8 mg per vial, exclusively for laboratory and research purposes.

+99.855% Purity

Third-Party Tested

COA Available

Additional information

Size

36 IU

99.95

5 in stock

Certificate of Analysis

Lab results

For a large part of our product range, we publish analysis certificates from independent laboratories, including Janoshik Independent Peptide Analytics.
The available reports can be found on our lab results page and are accessible to everyone.

What is HGH?

HGH (human growth hormone, somatotropin in chemical nomenclature) is a single polypeptide chain of 191 amino acids with a molecular weight of approximately 22.1 kDa. The chain folds into a four-helix bundle, the structural motif characteristic of single-chain cytokines. Two disulfide bridges determine the tertiary arrangement: Cys53 to Cys165 anchors a large loop in the middle, while Cys182 to Cys189 closes a small loop near the C-terminal end. This structure makes the compound a widely used model in the study of higher-order protein structure and conformational stability.

In research models, the target is the extracellular domain structure of the growth hormone receptor. In vitro, a single polypeptide chain binds two receptor copies via two spatially separated binding planes, after which receptor dimerization occurs and the JAK2 and STAT5 signaling pathways are activated in cell models. This two-step binding geometry makes the molecule a standard example of ligand-induced receptor dimerization in biophysics. Consequently, HGH is used as a model compound and reference substance in scientific research.

Research areas

In a laboratory context, HGH occurs in the following research areas, among others:

  • Research into ligand-receptor stoichiometry and receptor dimerization at isolated receptor domains in vitro.
  • Signal transduction research into the JAK2 and STAT5 axes in cell culture systems and reporter models.
  • Biophysical structure studies of the four-helix beam and the contribution of both disulfide bridges to conformational stability.
  • Structure-activity research on single-chain cytokines, in which helix surfaces are related to binding affinity.
  • Analytical method development and validation (SEC-HPLC, RP-HPLC, LC-MS, peptide mapping) with the polypeptide as the reference standard.
  • Stability and aggregation studies on freeze-dried protein preparations, including deamidation of asparagine and oxidation of methionine.

Each of these applications involves controlled laboratory or preclinical model research.

Usage & Disclaimer

• Intended solely for research purposes.

• Not for human use, diagnosis, or treatment.

• To be used only by qualified personnel in a controlled research environment.

• By purchasing this product, you confirm that you have read these terms and conditions and will follow proper research practices.

SpecificatieWaarde
MonsterHGH
SynoniemenHumaan groeihormoon; hGH; somatotropine (humaan); 191-aminozuur-polypeptide
CAS-nummer12629-01-5
Molecuulformule / gewichtC990H1528N262O300S7 / 22.125 Da
KlasseRecombinant polypeptide, eenketen-cytokine met vier-helix-bundel
VormGevriesdroogd lyofilisaat in verzegelde vial
Hoeveelheid per vial8 mg
Aantal vials per verpakking1
OpslagKoel en droog bewaren bij 2 tot 8 °C, beschermd tegen licht en vocht

Frequently Asked Questions

No. All products offered are strictly for laboratory research and analytical purposes only

They are not intended for human or animal consumption, nor are they for use in food, drugs, medical devices, or cosmetics.

We maintain rigorous quality standards through a multi-step verification process to ensure the highest analytical purity for your research:

  • Batch-Specific Testing: Every production batch undergoes comprehensive testing, including HPLC (High-Performance Liquid Chromatography) to verify purity and MS (Mass Spectrometry) to confirm identity.

  • Third-Party Validation: In addition to manufacturer COAs, we utilize independent third-party laboratories to verify that our products meet or exceed a purity standard of 99%.

  • Transparent Documentation: We provide a COA Library on our website where researchers can access and download the specific Certificates of Analysis for their products.

  • Controlled Storage: All materials are stored in temperature-controlled environments prior to shipping to prevent degradation and maintain molecular integrity.

Yes, we offer bulk pricing and wholesale opportunities for larger research requirements. If you are looking to purchase high volumes of specific compounds, please contact our support team or use our contact form to request a custom quote. We provide tiered discounts based on order quantity to support extensive or long-term laboratory studies.

For optimal stability and to maintain the integrity of your research materials, we recommend the following storage guidelines:

  • Short-term storage: Lyophilized (freeze-dried) peptides are stable at room temperature for a few weeks, but for best results, store them in a cool, dry place away from direct sunlight.

  • Long-term storage: For extended periods, store lyophilized peptides in a refrigerator (2°C to 8°C) or a freezer (-20°C) to prevent degradation.

  • Reconstituted peptides: Once a peptide has been dissolved in a bacteriostatic water or a similar solvent, it should be kept refrigerated and used within a short timeframe (typically 2–4 weeks) for maximum potency.

Always ensure the vials are tightly sealed to prevent moisture from entering.

Yes, we offer worldwide shipping to most countries. We utilize secure and discreet international shipping methods to ensure your research materials arrive safely and efficiently. You can see the specific shipping options and estimated delivery times for your country during the checkout process.